How to compare object using Not variable1 Is Nothing and variable1 IsNot Nothing in VB.NET. This can be confusing but once you get the syntax right it should be ok. I was trying to compare the object and trying to determing if object is null or not.

Method 1:

If variable1 IsNot Nothing Then
 'Your code
End If

OR Method 2:

If Not variable1 Is Nothing Then
 'Your code
End If

IsNot can also use to compare the two object to determine if they are the same object.

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